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KMID : 0377619630050030241
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Korean Jungang Medical Journal
1963 Volume.5 No. 3 p.241 ~ p.247
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Effects of physostigmine and atropine on the isolated uteri of Estrogen, Progesterone and Gonadotropine treated rats
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Abstract
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The administration of physostigmine and atropine on the isolated uteri of Estrogen, Progesterone. and Gonadotropine treated rats has revealed the following effects.
A. By the administration of physostigmine on the isolated uteri of Estrogen treated rats for 4, 10, 13, 15, 15, 16 and 20 days, the different action in each one occured as follows.
1. The isolated uterus of Estrogen non-treated rat. did not affect the response of uterine motility by the administration of physostigmine.
2. The isolated uterus of Estrogen treated rat for 4 days produced slight increase of amplitude and contraction of uterine motility by the administration of physostigmine.
3, The isolated _uterus of Estrogen treated rat for 10 days produced marked increase of amplitude, severe contraction and ascent of tonus of uterine motility by the administration of physostigmine.
4. The isolated uterus of Estrogen treated rat for 13 days produced gradual decrease of amplitude of uterine motility by the administration of physostigmine.
5. The isolated uteri of Estrogen treated rats for 16 and 20 days did not affect the response of uterine motility by the administration of physostigmine.
6. All action of physostigmine above listed 1, 2, 3, 4 and 5 were not complety blocked by the administration of atropine.
E. By the administration of physostigmine, specific actions did not occur in the isolated uteri of progesterone treated rats for 4, 10, 13, 15, 16 and 20 days.
C. By the administration of physostigmine, specifie actions did not occur in the isolated uteri of gonado-tropine treated rats for 4, 10, 13, 15, 16 and 20 days.
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